The A.30 variant of the coronavirus, detected in Angola and Sweden, is highly resistant to antibodies induced by the Pfizer and AstraZeneca vaccines, a new lab study has shown.
A team from Germany looked at the rare A.30 variant that was first recorded in Tanzania and later detected in several patients in Angola and Sweden this spring. They compared the mutation to the Beta and Eta variants. Beta was chosen because it has “the highest level” of resistance to antibodies, the researchers said.
According to the study published in the peer-reviewed journal Cellular & Molecular Immunology this week, the A.30 variant showed improved ability to enter most host cells, including kidney, liver, and lung cells.
The mutation “enters certain cell lines with increased efficiency and evades antibody-mediated neutralization,” the study found.
“In summary, A.30 exhibits a cell line preference not observed for other viral variants and efficiently evades neutralization by antibodies elicited by ChAdOx1 nCoV-19 [AstraZeneca] or BNT162b2 [Pfizer] vaccination.”
The variant also proved to be resistant to monoclonal drug Bamlanivimab, which is used for Covid-19 treatment, but was vulnerable to a cocktail of Bamlanivimab and Etesevimab.
A.30 has so far not been listed by the World Health Organization (WHO) as a variant of interest or concern, due to its low prevalence.
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source: RT
Împotriva articolelor redacției noastre, persoanele nemulțumite pot formula Contestație în termen de 10 zile de la publicarea articolului, la judecătoria Orășenească nr. 1 München Bayern Deutschland, in conformitate cu Legea federală Germană. Considerăm că nu se pot formula acțiuni la instanțele din România deoarece nici o persoană care activează în trustul nostru nu poate fi extrasă de sub jurisdicția federală germană. Considerăm că redacția noastră nu răspunde în fața autorităților din România ci doar celor federale sau civile germane. deoarece legea română nu are efecte de extraneitate asupra redacției chiar dacă subiectul știrilor face obiectul unor evenimente sau persoane din România și sunt scrise în limba română. Limba română nu este izvor de extraneitate a legii.
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